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ABILIFY More than half of people with bipolar disorder take second-generation/atypical antipsychotics on a regular basis to control mood. While effective, there is always a risk of adverse side effects. The list for antipsychotics is long, including dizziness, gastrointestinal distress, weight gain, sleepiness and seizures. The benefits generally outweigh the risks, but side effects are often listed as the main reason patients stop taking medication. However, one atypical antipsychotic seems to have advantages over others- aripiprazole (brand name- Abilify). Atypical antipsychotics are effective at treating mania in bipolar disorder. They can also reduce anxiety. Most of the medications work by balancing dopamine. Too much dopamine can lead to manic symptoms and psychosis. Too little can lead to depression. Atypical antipsychotics also affect serotonin levels and act as an antihistamine. Blocking histamine increases the sedation effect of antipsychotics Uses Aripiprazole is us